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PLATELET-RICH FIBRIN MATRIX (PRFM)

NEXT GENERATION PRP

WHAT IS PLATELET-RICH PLASMA (PRP)?

PRP, by definition refers to platelets in plasma, where the platelet concentration is generally considered to be twice the normal concentration in whole blood. Nowhere in the definition of PRP is there a description for including red blood cells (RBC) or white blood cells (WBC) – in fact, these cells should be removed as much as possible from a PRP preparation. Some kits that tout high platelet concentrations often do so at the expense of having contaminating RBCs or WBCs – these cells are known to have inflammatory and catabolic effects – just the opposite of the desired effect. If the PRP in the syringe has any tinge of pink or red, it is mostly likely that you are injecting a preparation that has RBC contamination.

 

The ideal PRP solution will be a golden, straw-like color.

WHAT IS SELPHYL® PRFM?

The SELPHYL® System is designed for the safe and rapid preparation of Platelet-rich Fibrin Matrix (PRFM) from a small sample of blood at the patient point of care. Many PRP systems require operator skill, have varying results and have extensive contamination with red blood cells and white blood cells. SELPHYL® removes virtually all contaminating cells and is independent of operator technique. PRP is converted to PRFM through a controlled process, creating a scaffold that serves to protect and preserve platelets.

 

Think of SELPHYL® PRFM as the next generation PRP.

Introducing the Future of PRP      SELPHYL® PRFM 

HOW IS SELPHYL® PRFM DIFFERENT?

The SELPHYL® System is a completely closed system and can convert PRP to PRFM with the addition of a precise amount of calcium chloride, which initiates the conversion of fibrinogen to fibrin, as part of the clotting cascade. The fibrin matrix serves as a three dimensional scaffold to maintain the platelets at the site of injection. The scaffold also serves to protect the platelets so their release of growth factors can be sustained over a longer period of time.

FIBRIN MATRIX SCAFFOLD IS KEY!

  • “Golden” Visual Guide to Quality

  • Purest PRP/PRFM

  • Closed-System

  • Secondary Proprietary Step

  • Converts PRP to PRFM

  • Calcium chloride allows for controlled fibrin polymerization

  • Scaffold is a biologic connector

  • Platelets are localized and viable

  • Sustained growth factor release

FEATURES

SELPHYL® Science

FIBRIN MATRIX

Watch Dr. Richard Goldfarb, MD demonstrate SELPHYL® PRFM's Ease-of-Use!

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The SELPHYL® System is designed to be used for the safe and rapid preparation of autologous platelet-rich-plasma (PRP) from a small sample of blood at the patient point of care. The PRP is mixed with autograft and/or allograft bone prior to application to a bony defect for improving handling characteristics.

SELPHYL®

940 Town Center Drive

Suite F-20

Langhorne, PA 19047

1.877.SELPHYL

Factor Medical Inc.

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